General Information

  • ID:  hor002909
  • Uniprot ID:  P42985
  • Protein name:  Oviductal motility-stimulating peptide
  • Gene name:  NA
  • Organism:  Leptinotarsa decemlineata (Colorado potato beetle) (Doryphora decemlineata)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Leptinotarsa (genus), Doryphorini (tribe), Chrysomelinae (subfamily), Chrysomelidae (family), Chrysomeloidea (superfamily), Cucujiformia (infraorder), Polyphaga (suborder), Coleoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  NA

Sequence Information

  • Sequence:  IAYKPE
  • Length:  6(1-6)
  • Propeptide:  IAYKPE
  • Signal peptide:  NA
  • Modification:  T6 Glutamic acid 1-amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Stimulates the contractions of the oviduct
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002909_AF2.pdbhor002909_ESM.pdb

Physical Information

Mass: 80920 Formula: C34H53N7O10
Absent amino acids: CDFGHLMNQRSTVW Common amino acids: AEIKPY
pI: 6.4 Basic residues: 1
Polar residues: 1 Hydrophobic residues: 2
Hydrophobicity: -66.67 Boman Index: -577
Half-Life: 20 hour Half-Life Yeast: 30 min
Half-Life E.Coli: >10 hour Aliphatic Index 81.67
Instability Index: 2473.33 Extinction Coefficient cystines: 1490
Absorbance 280nm: 298

Literature

  • PubMed ID:  2052497
  • Title:  Isolation, identification and synthesis of novel oviductal motility stimulating head peptide in the Colorado potato beetle, Leptinotarsa decemlineata.